Immunoglobulins

IgG: 75% of all immunoglobulins in body; Smallest but most common; neutralises toxins and bacteria; very important in fighting bacterial and viral infections.

 

IgA: 10-15% of all immunoglogulins in body; First immunological barrier against antigens that enter the mucous membranes. Found in areas of the body such the nose, breathing passages, digestive tract, ears, eyes, and vagina. Also found in saliva, tears, and blood.

 

IgM: The largest immunoglobulins found in the body. They are found in blood and lymph fluid and are the first type of antibody made in response to an infection. They also cause other immune system cells to destroy foreign substances.

 

IgD: Found in small amounts in the tissues that line the belly or chest. Main component of surface membranes and many B-cells, plays an important role in the lymphocyte-differentiation triggered by antigens.

 

IgE: Found in the lungs, skin, and mucous membranes. They cause the body to react against foreign substances such as pollen, fungus spores, and animal dander. They are involved in allergic reactions to milk, some medicines, and some poisons. Connects to: basophil mast cells, mucous membranes of the eyes and the bronchi.

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